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Many people believe the best approach to glioblastoma treatment is a comprehensive one, utilizing the most effective aspects of every treatment mode, including the latest drugs and surgery from conventional Western (allopathic) medicine to exotic botanicals and alternative healing. The hallmark of brain tumors is their heterogeneity; every patient and every tumor is different. Presented here are treatment options which have helped a wide variety of glioblastoma patients. These treatment options and data should be carefully reviewed to fit your particular circumstances and needs, so that you, in consultation with your doctor, can determine the best course of treatment. The best way to make good treatment decisions is to be well-informed.